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<article xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="1.3" article-type="other"><front><journal-meta><journal-id journal-id-type="issn">3051-2492</journal-id><journal-title-group><journal-title>ReAttach Affect Coach Journal</journal-title><abbrev-journal-title>ReAC</abbrev-journal-title></journal-title-group><issn pub-type="epub">3051-2492</issn><publisher><publisher-name>ReAttach Therapy International Foundation</publisher-name><publisher-loc>Netherlands</publisher-loc></publisher></journal-meta><article-meta><article-categories><subj-group><subject>Psychology</subject></subj-group></article-categories><title-group><article-title>ReAttach Protocol  for Adverse Childhood Experiences:  Nurturing Resilience and Strength </article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Zeestraten-Bartholomeus</surname><given-names>Paula</given-names></name><xref ref-type="aff" rid="AFF-1"/></contrib><contrib contrib-type="author"><name><surname>Bita</surname><given-names>Mohadeseh</given-names></name><xref ref-type="aff" rid="AFF-2"/></contrib><aff id="AFF-1">Director ReAttach Academy, President ReAttach Therapy International Foundation, Editor ReAttach Affect Coach Journal, Netherlands</aff><aff id="AFF-2">Student, Bu-Ali Sina University, Iran, Editor in ReAttach Affect Coach Journal, Netherlands</aff></contrib-group><pub-date-not-available/><volume>1</volume><issue>1</issue><fpage>33</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright @2025, Paula Zeestraten-Bartholomeus</copyright-statement><copyright-year>2025</copyright-year><copyright-holder>Paula Zeestraten-Bartholomeus</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0/</ali:license_ref><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><self-uri xlink:href="https://affectcoach.com/index.php/ReAC/article/view/18" xlink:title="ReAttach Protocol  for Adverse Childhood Experiences:  Nurturing Resilience and Strength ">ReAttach Protocol  for Adverse Childhood Experiences:  Nurturing Resilience and Strength</self-uri><abstract><p>Early childhood trauma is associated with higher risks of mental illness, addiction, suicide attempts, chronic health conditions, and even premature mortality in adulthood [1,2,3,4,5]. Due to chronic, toxic stress, the biological stress response systems are repeatedly activated, inducing elevated stress-related hormones and neuromodulators that negatively impact brain development [1,7,8,9]. Research suggests that learning, development, and health are at stake due to the dysregulation of various stress response systems, such as the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system, which can lead to various health issues. Exposure to any form of early childhood trauma is a transdiagnostic factor in the origin or development of psychological or psychosomatic complaints in adults [10]. It is, therefore, of the utmost importance to be trauma-sensitive in the approach and treatment of patients with chronic or complex problems. This ReAttach Protocol for Adverse Childhood Events is a guideline for all ReAttach Specialists and ReAttach Affect Coaches who want to work in a trauma-sensitive manner without shifting the focus to trauma.</p></abstract><kwd-group><kwd>ReAttach</kwd><kwd>W.A.R.A.</kwd><kwd>Forgive and Forget Hood</kwd><kwd>Attachment</kwd><kwd>New Mind Creation</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>File created by JATS Editor</meta-name><meta-value><ext-link ext-link-type="uri" xlink:href="https://jatseditor.com" xlink:title="JATS Editor">JATS Editor</ext-link></meta-value></custom-meta><custom-meta><meta-name>issue-created-year</meta-name><meta-value>2025</meta-value></custom-meta></custom-meta-group></article-meta></front><body><sec><title>Introduction</title><p>Adverse Childhood Experiences (ACEs) have profound and lasting impacts on psychological, neurological÷1, and physical development. While the damaging effects of toxic stress are well-documented, there remains a gap in trauma-informed protocols that both avoid re-traumatization and promote resilient development <xref ref-type="bibr" rid="BIBR-11">[11]</xref>. This paper introduces the ReAttach Protocol for ACEs, a transdiagnostic and trauma-sensitive approach that aims to bridge developmental gaps through the structured provision of Positive Childhood Experiences (PCEs). Although adverse childhood experiences might cause many problems, such as heightened anxiety, mood disorders, and cognitive dysfunction, we also know that a supportive (family) environment and tailored interventions can mitigate these challenges <xref ref-type="bibr" rid="BIBR-11">[11]</xref>.</p><p>Survivors of childhood trauma develop differently than they would have if no trauma had occurred. Their current perception and thought patterns are natural because they have no other frame of reference to compare them to. However, this does not mean that they cannot or would not want to learn to think differently. It mainly indicates that they do not form certain neural connections and will not ask for help to fill the gaps in their development.</p><p>Survivors of childhood trauma whom positive childhood experiences have shielded show better overall developmental outcomes <xref ref-type="bibr" rid="BIBR-12">[12]</xref>. These positive childhood experiences (PCEs) might help us formulate training goals we can offer in our ReAttach sessions as critical factors for resilience and positive development <xref ref-type="bibr" rid="BIBR-13">[13]</xref><xref ref-type="bibr" rid="BIBR-14">[14]</xref>. More specifically, PCEs were associated with less psychopathology, such as anxiety, depression, PTSD, personality disorders, addiction, affective lability, sleep problems, and learning disorders [14,15]. By investing in PCEs to improve supportive relationships, enrich experiences, and create growth opportunities, we can help patients with early childhood trauma lead happier, healthier, and more successful lives in adulthood <xref ref-type="bibr" rid="BIBR-15">[15]</xref><xref ref-type="bibr" rid="BIBR-16">[16]</xref>. Stable, nurturing relationships and environment form an important subset of resilience factors that could moderate the impact of early childhood trauma.</p><p>Recent longitudinal studies have shown that the positive effect of PCEs is strongest when they are cumulative <xref ref-type="bibr" rid="BIBR-17">[17]</xref>. This outcome would mean that the more PCE deficiencies we can resolve during ReAttach sessions, the stronger the positive impact on the personal growth of our clients. Not having experienced PCEs yet is a vulnerability, but it also offers opportunities, provided we pay sufficient attention to this. These findings are entirely in line with the New Mind Creation protocol <xref ref-type="bibr" rid="BIBR-18">[18]</xref>, which will play a key role in the treatment of individuals with early childhood trauma.</p><p>In summary, for individuals with early childhood trauma, it is crucial to detect the gap between the development they have experienced and the development they might have experienced if circumstances had been cumulatively better.</p><sec><title>Spectrum of Early Childhood Trauma: Pervasive Development Disorders</title><p>Early childhood trauma is a transdiagnostic factor in a wide range of mental and psychosomatic disorders. Just as cumulative negative childhood experiences can lead to significantly more harm, positive experiences and protective factors can have cumulative beneficial effects. We argue that, as in Autism Spectrum Disorders (ASD), there must be a spectrum of pervasive early childhood trauma development disorders, ranging from limited damage to grave consequences for the person in question. We will discuss the transdiagnostic factors here, which will be placed within this spectrum as underlying factors that either threaten or optimize development.</p><sec><title>Dissociation</title><p>Dissociation is a coping mechanism that enables patients to compartmentalize aspects of their experiences in response to an overwhelming or stressful event <xref ref-type="bibr" rid="BIBR-20">[20]</xref><xref ref-type="bibr" rid="BIBR-21">[21]</xref><xref ref-type="bibr" rid="BIBR-22">[22]</xref>. There is a broad spectrum of dissociative disorders, of which defensive exclusion, when stress levels become too high, is widespread: many people experience dissociation during their lives. Becoming so absorbed in an activity that one loses awareness of the surroundings is a form of dissociation or an escape from reality. After an accumulation of adverse events, individuals with early childhood trauma can learn to use dissociation as a way to deal with stressful experiences. Dissociative disorders occur when dissociation becomes distressing and problematic and affects daily life functioning, for instance, in derealisation (feeling detached or separate from the world) and depersonalization (feeling disconnected from yourself or parts of yourself). Dissociation might also facilitate identity alteration and confusion, as in Dissociative Identity Disorders <xref ref-type="bibr" rid="BIBR-20">[20]</xref><xref ref-type="bibr" rid="BIBR-21">[21]</xref><xref ref-type="bibr" rid="BIBR-22">[22]</xref>.</p><p>Taken together, dissociation is a maladaptive coping mechanism that can be persistent and can interfere with developing a coherent view of self, others, and the world. In the treatment of dissociation as a transdiagnostic factor, a tailored, multimodal intervention focusing on identity integration and adaptive coping styles is required <xref ref-type="bibr" rid="BIBR-23">[23]</xref><xref ref-type="bibr" rid="BIBR-24">[24]</xref><xref ref-type="bibr" rid="BIBR-25">[25]</xref>.</p></sec><sec><title>Affective Empathy</title><p>Experiencing childhood adversity has detrimental effects on affective empathy <xref ref-type="bibr" rid="BIBR-26">[26]</xref><xref ref-type="bibr" rid="BIBR-27">[27]</xref>. Research with fMRI suggests that in individuals with low levels of affective empathy, the mirror neuron system is altered <xref ref-type="bibr" rid="BIBR-28">[28]</xref>. Furthermore, research found that adolescents with weak cognitive empathy manage to compensate for or develop this social cognitive skill <xref ref-type="bibr" rid="BIBR-29">[29]</xref>. However, as far as affective empathy is concerned, it seems as if disruptions to affective empathy last a lifetime <xref ref-type="bibr" rid="BIBR-29">[29]</xref>.</p><p>Reviewing the literature, the protective nature of PCEs appears to align more closely with cognitive empathy (requiring perspective-taking and imagination) than affective empathy (feeling someone else's distress). One possible explanation might be the fact that cognitive compensations for empathy do not require a properly functioning mirror neuron system, as is the case for affective empathy.</p></sec><sec><title>Sensory Over-Responsivity (SOR)</title><p>Early childhood trauma can cause hypervigilance and a disturbed balance between excitation–and inhibition <xref ref-type="bibr" rid="BIBR-30">[30]</xref>. This disturbance increases SOR and the intolerance to stress and sensory stimuli. A clinical trial by Cracknell et al. <xref ref-type="bibr" rid="BIBR-30">[30]</xref> suggests a high-dose Vitamin-B6 to support inhibition and restore the disturbed brain balance. Interventions, such as ReAttach <xref ref-type="bibr" rid="BIBR-14">[14]</xref>, aimed at improving sensory processing, are important to reduce and prevent SOR in the future.</p></sec><sec><title>Early Maladaptive Schemas (EMS)</title><p>Individuals with early childhood trauma can develop Early Maladaptive Schemas according to Young's schema theory <xref ref-type="bibr" rid="BIBR-31">[31]</xref><xref ref-type="bibr" rid="BIBR-32">[32]</xref> when their basic affective needs are not met. Young <xref ref-type="bibr" rid="BIBR-31">[31]</xref><xref ref-type="bibr" rid="BIBR-32">[32]</xref> mentions five basic affective needs:</p><p>• Secure attachments to others (safety, stability, nurturance, and acceptance);</p><p>• Autonomy, competence, and sense of identity;</p><p>• Freedom to express valid needs and emotions;</p><p>• Spontaneity and play;</p><p>• Realistic limits and self-control.</p><p>Young <xref ref-type="bibr" rid="BIBR-31">[31]</xref><xref ref-type="bibr" rid="BIBR-32">[32]</xref> described five EMS domains with eighteen maladaptive schemas:</p></sec><sec><title>Disconnection and Rejection</title><p>- Abandonment;</p><p>- Mistrust/abuse;</p><p>- Emotional deprivation;</p><p>- Defectiveness/shame;</p><p>- Social isolation</p><p>Impaired Autonomy and Achievement</p><p>- Dependency/incompetency;</p><p>- Vulnerability to harm/illness;</p><p>- Enmeshment/undeveloped self;</p><p>- Failure</p><p>Impaired Limits</p><p>- Entitlement/grandiosity;</p><p>- Lack of self-control/self-discipline</p><p>Other-directedness</p><p>- Subjugation;</p><p>- Self-sacrifice;</p><p>- Approval/recognition-seeking</p><p>Hypervigilance and Inhibition</p><p>- Negativity/pessimism;</p><p>- Emotional inhibition;</p><p>- Unrelenting standards;</p><p>- Punitiveness</p><p>Correcting maladaptive coping strategies is difficult, since individuals with maladaptive coping styles focus on schema-congruent information rather than seeking exposure to experiences contradicting them. Besides, due to biological changes through adverse events, such as inflammatory responses, updating and correcting maladaptive schemas is difficult for the brain <xref ref-type="bibr" rid="BIBR-33">[33]</xref>.</p><p>Negative EMSs predict helplessness, hopelessness, and worthlessness <xref ref-type="bibr" rid="BIBR-31">[31]</xref><xref ref-type="bibr" rid="BIBR-33">[33]</xref><xref ref-type="bibr" rid="BIBR-34">[34]</xref><xref ref-type="bibr" rid="BIBR-35">[35]</xref>. A recent study showed that the schemas of Defectiveness/Shame and Social Isolation / Alienation were strongly associated with depression. Schema-congruent information, thus the prediction of being inferior, unlovable, or not belonging, leads to maladaptive coping styles, including avoidance, overcompensation, or surrendering <xref ref-type="bibr" rid="BIBR-36">[36]</xref>.</p><p>In contrast, securely attached persons are aware of their negative affect and process distress with self-compassion and ask for help if they need support <xref ref-type="bibr" rid="BIBR-37">[37]</xref>.</p></sec><sec><title>Well-being comparisons to better-off standards</title><p>Individuals who have experienced early childhood trauma see themselves, others, and society through different eyes because of their life experiences. They often feel different from people who have not experienced so many bad things and are less able to identify with the unburdened individuals. If they engage in well-being comparisons to better-off standards, they may perceive themselves as falling short, accompanied by feelings of inadequacy or self-doubt <xref ref-type="bibr" rid="BIBR-38">[38]</xref><xref ref-type="bibr" rid="BIBR-39">[39]</xref><xref ref-type="bibr" rid="BIBR-40">[40]</xref>. These negative thought patterns can lead patients to become trapped in a vicious circle of fear <xref ref-type="bibr" rid="BIBR-41">[41]</xref>. These negative thought patterns can lead patients to become trapped in a vicious circle of fear <xref ref-type="bibr" rid="BIBR-41">[41]</xref>. An external locus of control reinforces these aversive comparisons, which can lead to confirmation of maladaptive schemas, making it even more challenging to adjust <xref ref-type="bibr" rid="BIBR-39">[39]</xref><xref ref-type="bibr" rid="BIBR-42">[42]</xref><xref ref-type="bibr" rid="BIBR-43">[43]</xref>.</p></sec><sec><title>Affective Isolation and Embodied Emotions</title><p>The avoidance of experiencing or expressing emotions is a defense mechanism that helps individuals with early childhood trauma create a seemingly calm external presentation and maintain the appearance of emotional stability. This coping style just masks the underlying emotional turmoil within. Affective isolation <xref ref-type="bibr" rid="BIBR-20">[20]</xref> and denial of traumatic memories and events will not fool the body: emotional experiences have a deep impact on our bodily states. Multisensory integration of exteroceptive, proprioceptive, and interoceptive sensory inputs may lead to dysfunctional threat perception and experiences <xref ref-type="bibr" rid="BIBR-44">[44]</xref><xref ref-type="bibr" rid="BIBR-45">[45]</xref>. According to Giraud et al. <xref ref-type="bibr" rid="BIBR-45">[45]</xref>, the somatosensory system could be considered a mediator/gatekeeper through which emotions pass with a dissociable effect of arousal and affective valence.</p><p>Research has shown that simple bodily exercises can enhance embodied cognitive restructuring <xref ref-type="bibr" rid="BIBR-46">[46]</xref>, suggesting the integration of body-oriented exercises into existing protocols or as a complement to the treatment regimen.</p></sec></sec><sec><title>ReAttach Protocol for Early Childhood Trauma</title><p>A spectrum of early childhood trauma and pervasive developmental issues requires a tailored, integrative approach. ReAttach is a method that requires proximity, and that can be very difficult for many victims of adverse events to trust. Taking time for psycho-education and introducing ReAttach techniques through short-term self-regulation exercises can help build the client's confidence. In general, it is essential not to initiate social cognitive training too soon and to allocate more time for preparation before the first ReAttach session.</p><sec><title>Validation of self-control</title><p>ReAttach Affect Coaches can help clients develop more self-control by offering exercises that introduce the ReAttach technique. A first, simple exercise is to have the client regulate their own arousal by drumming at a fast tempo or pressing with the index and middle fingers. The Forgive and Forget Hood can be used as a self-regulation exercise to clear the mind and the W.A.R.A. to learn how to decrease sensory overresponsiveness or negative affect.</p></sec><sec><title>New Mind Creation Procedure</title><p>We advise ReAttach Affect Coaches to first use the New Mind Creation procedure <xref ref-type="bibr" rid="BIBR-50">[50]</xref>, including checking all the conditions that must be met before applying the New Mind Creation technique:</p><list list-type="bullet"><list-item><p>Activated mirror neuron system</p></list-item><list-item><p>Automated sensory integration</p></list-item><list-item><p>Social cognitive training</p></list-item><list-item><p>Trained or restored optimism bias</p></list-item><list-item><p>Reconnect with positive affect</p></list-item></list><p>With an activated mirror neuron system, social cognitive training enables the ReAttach Affect Coach to help patients develop affective empathy by training cognitive empathy under optimal arousal and sensory integration.</p><p>ReAttach utilizes identifications to transition adaptive skills from an external locus of control to an internal locus of control, thereby bringing them within the reach of learning ability.</p><p>In the early childhood trauma protocol, extra attention is paid to identification with a loving observer who can look lovingly and attentively at all aspects of the self. The purpose of this is to enhance the internal organization of patients, enabling a coherent sense of self.</p><p>As mentioned earlier, it is imperative to pay special attention to body-oriented interventions that help release the negative, embodied emotions held in the body through a combination of identifications and Cognitive Bias Modification (CBM) <xref ref-type="bibr" rid="BIBR-14">[14]</xref>. The patient can integrate these somatic experiences by engaging in motor imagery of actions to release the body's fight, flight, or freeze responses. In a sustained flight response, a patient might run very fast during motor imagery, kick or hit very hard during a fight response, and warm up and bask in the sun during the freeze response. All these examples aim to integrate traumatic somatic experiences.</p><p>In the New Mind Creation session, ReAttach Affect Coaches focus on filling the gap between optimal development and the current neuropathways the patient has been walking to promote secure attachment and Growth Mindset <xref ref-type="bibr" rid="BIBR-50">[50]</xref>. Although the primary goal of the New Mind Creation is to promote secure attachment, the technique can also be applied after training to facilitate cognitive restructuring within a secure attachment framework. An example is learning to trust schema-incongruent information (during NMC) or being able to tolerate the exposure of toxic shame while taking the perspective of the mirror image and looking to the inner self (CBM1/NMC combination). Practicing exploration during the NMC is a boost for the Growth Mindset and is promising for patients with early childhood trauma or complex problems.</p><table-wrap id="table-gidaku" ignoredToc=""><table frame="box" rules="all"><tr><td colspan="1" rowspan="1" style="" align="left" valign="top">Technique</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Objective</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Application</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Notes</td></tr><tr><td colspan="1" rowspan="1" style="" align="left" valign="top">Forgive and Forget Hood</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Alleviate persistent thoughts</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Used in early sessions to clear mental clutter</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Client can practice independently</td></tr><tr><td colspan="1" rowspan="1" style="" align="left" valign="top">W.A.R.A.</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Regulate negative emotions and Sense of Reality (SOR)</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Applied under mild arousal to recalibrate responses</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Use after initial psychoeducation</td></tr><tr><td colspan="1" rowspan="1" style="" align="left" valign="top">New Mind Creation</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Build secure attachment and schema restructuring</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Applied after mirror system and optimism are activated</td><td colspan="1" rowspan="1" style="" align="left" valign="top">Requires trust and coach-client bond</td></tr></table></table-wrap></sec></sec></sec><sec><title>Discussion</title><p>The ReAttach protocol for early childhood trauma is written for a spectrum of individuals who have experienced adverse events with varying degrees of severity impacting their lives. Early childhood trauma often plays a role in patients with complex psychological or psychosomatic problems, even if it is not recognized as such or even denied <xref ref-type="bibr" rid="BIBR-20">[20]</xref><xref ref-type="bibr" rid="BIBR-21">[21]</xref>. We suggest that there might be a spectrum of early childhood trauma and pervasive developmental disorders, with dissociation, affective empathy, sensory overresponsiveness (SOR), Early Maladaptive Schemas (EMS), welfare comparisons, and affective isolation being cited as transdiagnostic factors.</p><p>The ReAttach protocol for early childhood trauma is a tailored, integrative approach that requires proximity, which can be difficult for ACE victims. There, we explicitly emphasized the importance of psychoeducation and self-regulation exercises to validate the need for self-control. The New Mind Creation procedure is described as a key component of the protocol, with attention paid to the prerequisites that must be met before the technique can be applied. To release negative, embodied emotions in support of building adaptive schemas, we suggest integrating body-oriented exercises under the secure attachment of the New Mind Creation technique.</p></sec><sec><title>Conclusion</title><p>Although Adverse Childhood Events have a devastating influence on the lives of many, Positive Childhood Events can help survivors mitigate the toxicity in all developmental domains. ReAttach Affect Coaches can use this ReAttach Protocol for Adverse Childhood Events to provide victims with cumulative Positive Childhood Experiences, helping them fill developmental gaps and upgrade maladaptive schemas.</p><p>The ReAttach protocol provides a trauma-informed and neurodevelopmentally-informed strategy that turns adverse childhood experiences into avenues for healing and personal growth. By integrating PCEs within organized therapeutic interactions, ReAttach Affect Coaches facilitate the cultivation of resilience, self-regulation, and a cohesive self-identity. Utilizing a mix of cognitive restructuring, embodied techniques, and empathic connection, this protocol plays a key role in addressing developmental gaps caused by early adversity.</p></sec><sec><title>Declaration of interest</title><p>Paula Zeestraten-Bartholomeus is developer of ReAttach, W.A.R.A., the New Mind Creation and the Forgive and Forget Hood.</p></sec></body><back><ref-list><title>References</title><ref id="BIBR-1"><element-citation publication-type="article-journal"><article-title>Patterns of Adverse Childhood Experiences and Neurocognitive Development</article-title><source>JAMA pediatrics</source><volume>178</volume><issue>7</issue><person-group person-group-type="author"><name><surname>Yu</surname><given-names>J.</given-names></name><name><surname>Haynie</surname><given-names>D.L.</given-names></name><name><surname>Gilman</surname><given-names>S.E.</given-names></name></person-group><year>2024</year><fpage>678</fpage><lpage>687</lpage><page-range>678-687</page-range><pub-id pub-id-type="doi">10.1001/jamapediatrics.2024.1318</pub-id><ext-link xlink:href="10.1001/jamapediatrics.2024.1318" ext-link-type="doi" xlink:title="Patterns of Adverse Childhood Experiences and Neurocognitive Development">10.1001/jamapediatrics.2024.1318</ext-link></element-citation></ref><ref id="BIBR-2"><element-citation publication-type="article-journal"><article-title>Association of childhood adversity with morbidity and mortality in US adults: a systematic review</article-title><source>JAMA Pediatr</source><volume>175</volume><issue>12</issue><person-group person-group-type="author"><name><surname>Grummitt</surname><given-names>L.R.</given-names></name><name><surname>Kreski</surname><given-names>N.T.</given-names></name><name><surname>Kim</surname><given-names>S.G.</given-names></name><name><surname>Platt</surname><given-names>J.</given-names></name><name><surname>Keyes</surname><given-names>K.M.</given-names></name><name><surname>McLaughlin</surname><given-names>K.A.</given-names></name></person-group><year>2021</year><fpage>1269</fpage><lpage>1278</lpage><page-range>1269-1278</page-range><pub-id pub-id-type="doi">10.1001/jamapediatrics.2021.2320</pub-id></element-citation></ref><ref id="BIBR-3"><element-citation publication-type="article-journal"><article-title>The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis</article-title><source>Lancet Public Health</source><volume>2</volume><issue>8</issue><person-group person-group-type="author"><name><surname>Hughes</surname><given-names>K.</given-names></name><name><surname>Bellis</surname><given-names>M.A.</given-names></name><name><surname>Hardcastle</surname><given-names>K.A.</given-names></name></person-group><year>2017</year><pub-id pub-id-type="doi">10.1016/S2468-2667(17)30118-4</pub-id></element-citation></ref><ref id="BIBR-4"><element-citation publication-type="article-journal"><article-title>Adverse childhood experiences and associated health outcomes: a systematic review and meta-analysis</article-title><source>Child Abuse Negl</source><volume>97</volume><issue>104127</issue><person-group person-group-type="author"><name><surname>Petruccelli</surname><given-names>K.</given-names></name><name><surname>Davis</surname><given-names>J.</given-names></name><name><surname>Berman</surname><given-names>T.</given-names></name></person-group><year>2019</year><pub-id pub-id-type="doi">10.1016/j.chiabu.2019.104127</pub-id></element-citation></ref><ref id="BIBR-5"><element-citation publication-type="article-journal"><article-title>Adverse childhood experiences and premature mortality through mid-adulthood: a five-decade prospective study</article-title><source>Lancet Reg Health Am</source><volume>15</volume><issue>100349</issue><person-group person-group-type="author"><name><surname>Yu</surname><given-names>J.</given-names></name><name><surname>Patel</surname><given-names>R.A.</given-names></name><name><surname>Haynie</surname><given-names>D.L.</given-names></name></person-group><year>2022</year><pub-id pub-id-type="doi">10.1016/j.lana.2022.100349</pub-id></element-citation></ref><ref id="BIBR-6"><element-citation publication-type="article-journal"><article-title>Developmental traumatology: the psychobiological development of maltreated children and its implications for research, treatment, and policy</article-title><source>Dev Psychopathol</source><volume>13</volume><issue>3</issue><person-group person-group-type="author"><name><surname>Bellis MD</surname></name></person-group><year>2001</year><fpage>539</fpage><lpage>564</lpage><page-range>539-564</page-range><pub-id pub-id-type="doi">10.1017/S0954579401003078</pub-id></element-citation></ref><ref id="BIBR-7"><element-citation publication-type="article-journal"><article-title>Committee on Psychosocial Aspects of Child and Family Health; Committee on Early Childhood, Adoption, and Dependent Care; Section on Developmental and Behavioral Pediatrics. 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